Genome-wide identification of targets of the drosha-pasha/DGCR8 complex
نویسندگان
چکیده
منابع مشابه
Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.
Drosha is a type III RNase, which plays a critical role in miRNA biogenesis. Drosha and its double-stranded RNA-binding partner protein Pasha/DGCR8 likely recognize and cleave miRNA precursor RNAs or pri-miRNA hairpins cotranscriptionally. To identify RNAs processed by Drosha, we used tiling microarrays to examine transcripts after depletion of drosha mRNA with dsRNA in Drosophila Schneider S2 ...
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Identification of the mRNA targets of tRNA-specific regulation using genome-wide simulation of translation
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ژورنال
عنوان ژورنال: RNA
سال: 2009
ISSN: 1355-8382
DOI: 10.1261/rna.1319309